In this comprehensive collection of essays, most of which appear for the first time, eminent scholars from many disciplines—philosophy, economics, sociology, political science, demography, theology, history, and social psychology—examine the causes, nature, and consequences of present-day consumption patterns in the United States and throughout the world.

Recent data show that catastrophic events during one cell cycle can cause massive genome damage producing viable clones with unstable genomes. This is in contrast with the traditional view that tumorigenesis requires a long‐term process in which mutations gradually accumulate over decades. These sudden events are likely to result in a large increase in genomic diversity within a relatively short time, providing the opportunity for selective advantages to be gained by a subset of cells within a population. This genetic diversity (...) amplification, arising from a single aberrant cell cycle, may drive a population conversion from benign to malignant. However, there is likely a period of relative genome stability during the clonal expansion of tumors – this may provide an opportunity for therapeutic intervention, especially if mechanisms that limit tolerance of aneuploidy are exploited. (shrink)

When we hear about a transgression, we may consider whether the perpetrator’s individual circumstances make their transgression more understandable or excusable. Mitigating circumstances may reduce the severity of punishment that is deemed appropriate, both intuitively and legally. But importantly, in courts of public opinion and of law, mitigating information is typically presented only after information about a perpetrator’s transgression. We explore whether this sequence influences the force of mitigating evidence. Specifically, in two studies, we examined whether presenting evidence about a (...) perpetrator’s background before or after evidence of their violation influenced how severely U.S. participants punished perpetrators. In Study 1 (N = 132), evidence about the perpetrator’s mitigating circumstances reduced punishment only when it was presented before evidence about the perpetrator’s violation. Study 2 (N = 316) additionally revealed this moderating effect of presentation order across a variety of premeditated and impulsive violations. These findings are consistent with person-centered theories of punishment and with the Story Model of adjudication. (shrink)

Background Implementation science presents ethical issues not well addressed by traditional research ethics frameworks. There is little empirical work examining how clinicians whose work is affected by implementation studies view these issues. Accordingly, we interviewed clinicians working at sites participating in an implementation study seeking to improve patient handoffs to the intensive care unit (ICU).Methods We performed semi-structured interviews with 32 clinicians working at sites participating in an implementation study aiming to improve patient handoffs from the operating room to the (...) ICU. We analyzed the interviews using an iterative coding process following a conventional content analysis approach.Results Clinicians’ greatest concern about involvement was possible damage to interpersonal relations with more senior clinicians. They were divided about whether informed consent from clinicians was necessary but were satisfied with the study’s approach of sending out mass communications about the study. They did not think opting out of the implementation portion of the study was feasible but saw this inability to opt out as unproblematic because they equated the study with routine quality improvement. Those clinicians who helped launch the study at their sites recounted several different ways of doing so beyond simply facilitating access.Conclusions The risks that clinicians identified stemmed more from their general status as employees than their specific work as clinicians. Implementation researchers should be attuned to the ethical ramifications of involving employees of varying ranks. Implementation researchers using hybrid designs should also be sensitive to the possibility that practitioners affected by a study will equate it with quality improvement and overlook its research component. Finally, the interactions that go into facilitating an implementation study are more various than the “gatekeeping” typically discussed by research ethicists. More research is needed on the ethics of the myriad interactions that are involved in making implementation studies happen. (shrink)

Francis Bacon wrote of his method of eliminative induction that it was "a new and certain road for the mind to take" and that it would "establish degrees of certainty". I argue that Bacon's method is not certain in either of two different senses of "certain": (a) resulting in maximally justified conclusions or (b) being as secure as a deductively valid argument.

New B-Theorists of language, while conceding the untranslatability of tensed sentences by tenseless sentences, deny that the ineliminability of tense implies the reality of tensed facts. Thus, New BTheorist Nathan Oaklander explains, For a variety of reasons, ... recent defenders of the tenseless view have come to embrace the thesis that tensed sentences cannot be translated by tenseless ones without loss of meaning. Nevertheless, recent detensers have denied that the ineliminability of tensed language and thought entails the reality of temporal (...) properties. ... Tensed discourse is indeed necessary for timely action, but tensed facts are not, since the truth conditions of tensed sentences can be expressed in a tenseless meta-language that describes unchanging temporal relations between and among events. (shrink)

Recent critiques of methodological naturalism (MN) claim that it fails by conflicting with Christian belief and being insufficiently humble. We defend MN by tracing the real history of the debate, contending that the story as it is usually told is mythic. We show how MN works in practice, including among real scientists. The debate is a red herring. It only appears problematic because of confusion among its opponents about how scientists respond to experimental anomalies. We conclude by introducing our preferred (...) approach, Science‐Engaged Theology. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:GOD'S KNOWLEDGE OF FUTURE CONTINGENTS: A REPLY TO WILLIAM LANE CRAIG DAVID B. BURRELL, c.s.c. University of Notre Dame Notre Dame, Indiana IT IS FORTUNATE that other duties kept me from responding to William Lane Craig's "Aquinas on God's Knowledge of Future Contingents" when it came out (Thomist 54 [1990]: 33-79), for my initial perusal found me at once impressed and dismayed, and quite unable to disentangle (...) the two responses. A more careful subsequent reading allows me, I believe, to pinpoint where he goes wrong in reaching the conclusion which he does, yet to do so in such a way as to send readers back to an essay which is otherwise quite remarkable in the way it learns from Aquinas and offers us useful ways to read him on these perplexing issues. In doing so, he corrects many a misreading, and amasses sufficient textual and conceptual clarifications as almost to correct his own misreading. And best of all, I can hope that my rejoinder will send readers back to Aquinas above all. Indeed, one cannot but feel that the current climate of controversy regarding the proper understanding of his nuanced synthesis in philosophical theology would please Aquinas far more than attempts earlier in this century to distill it all into a " doctrine." Craig's conclusion reads: In maintaining that God's knowledge is the cause of everything God knows, Thomas transforms the universe into a nexus which, though freely chosen by God, is causally determined from above, thus eliminating human freedom (79). I shall claim that he reaches this conclusion only because ( 1) he presumes God's knowledge to be propositional knowing (52-53), 317 318 DAVID B. BURRELL, C.S.C. even though he asserts that it is not (60, n.61); and (2) that such a presumption leads him to overlook the vast difference between scientia visionis and scientia simplicis intelligentiae, though he insists on the difference and formulates it nicely in parallel with practical and speculative knowing in God (40). Such presumptions about divine knowing are not uncommon, of course, and what they lead to is one's overlooking what Josef Pieper called the "hidden element in the philosophy of St. Thomas "-creation. Indeed, my critique could begin there, remarking how Craig's careful delineation of Aquinas on God's eternal knowing of contingent things proceeds oblivious of the central fact that God's knowing in such cases is that of a creator (" In summary, then, Thomas has appealed e%clusively to the tradition of God's timelessness in order to defuse the threat of fatalism" [61, emphasis mine]). The simple observation that the God in question is always the free creator of all-that-is would have allowed him to see that Aquinas does not make the relation of God to contingents turn solely on that of an eternal knower of temporal things, but that the eternity/time relation subserves that of creator/creature. (This ordering is the more crucial, we shall see, for its power to correct the endemic tendency to equate " eternal " with " timeless," which Craig manifests throughout.) And despite Pieper's reminder that creation is largely hidden, it remains sufficiently present to a careful reader that Craig must indeed confront it at the end. Yet by the time he does so, his earlier presumptions have led him to complain that Aquinas's insistence that "God's knowledge is the causa essendi of the things that are going to happen... seems nearly unintelligible " (73). Indeed what I shall offer as the key to resolving his crucial dilemmas, and so overturning his stated conclusion, Craig introduces as a " final issue [which] threatens to undermine Thomas's attempt to preserve contingency in the face of divine knowledge, [viz.] his doctrine that God's knowledge is the cause of its objects rather than the objects' being the cause of God's knowledge" (70-71). The theologian in me would prefer to begin right here, with the radical eruption into an Aristotelian world of a free creator, GOD'S KNOWELDGE OF FUTURE CONTINGENTS 319 whose relation to the universe is indeed such as to turn our sense of knowing inside-out.1... (shrink)

While I may have misunderstood certain points in Craig's Molinist theodicy, a careful reading of my article will show that Craig is incorrect in his claim that I have failed to evaluate his proposal on the basis of its asserted standard: plausibility. The heart of my argument is that Craig's theodicy is implausible because it fails to provide a credible explanation of the culpability of all non-believers. In this rejoinder I try to show (1) why an evidentialist exoneration of reflective (...) disbelievers (in Christ) also applies, contra Craig, to the unevangelized; and (2) that an evidentialist account of reflective disbelief is more plausible than Craig's sinful-resistance account. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:Peirce on Realism and Idealism by Robert LaneAaron B. WilsonPeirce on Realism and Idealism Robert Lane. Cambridge UP, 2018.Robert Lane's Peirce on Realism and Idealism is the ultimate secondary source for those who wish to engage the forms of realism and idealism that Peirce develops over the course of his writings. Lane could not have given his monograph a more concise and descriptive title. He (...) never strays from the topics of realism and idealism, and it is remarkably complete. It includes extensive discussion on Peirce's basic realism (Lane's term) as well as his extreme scholastic realism (Peirce's term), his basic idealism (Lane's term), and his objective idealism (Peirce's term). It might not be the best resource for those interested in the historical influences on Peirce's forms of realism and idealism. For instance, if one is interested mainly in Peirce's extreme scholastic realism and its roots in scholastic philosophy, Mayorga (2007)1 might still be a more useful resource. Also, Lane leaves much to be said about the epistemological underpinnings of Peirce's forms of realism and idealism. Peirce's theory of perception and his critical common-sensism do not get much attention. Also, there is much in Peirce's later semeiotic writings that could have been brought to bear on the issues.However, I do not see any of these omissions as failures of Lane's work. As I read it, the book's central aims are to determine the following: (1) what metaphysical views did Peirce hold, (2) when did he hold them, (3) are they consistent with one another, and (4) what is the textual evidence that he held them as such. With respect to these aims, Peirce on Realism and Idealism exhibits the gold standard of Peirce scholarship: it is remarkably sensitive to dates, different writings, and contexts of writings, and the reader gets a strong impression that Lane has not left any stone unturned—that he had at least skimmed every word in every lecture, published writing, letter, and unpublished manuscript that Peirce produced.Although the book contains some interpretations about which I have some reservations, which I describe further on, I agree with most of its central claims. This includes the claim that, despite various developments, Peirce had always subscribed to "basic realism": the thesis that there are things independent of what anyone thinks about them. A whole chapter is dedicated to showing that Peirce's 1868–1869 "anti-Cartesian" papers are consistent with basic realism, and I found that chapter very helpful. Another thesis that Lane defends, and that I strongly agree with, is that Peirce held a representationalist view of truth. Truth as "correspondence" with reality is one of two [End Page 107] key aspects of Peirce's account of truth (the other being, as Lane calls it, an "investigative aspect"). After works by Christopher Hookway, Cheryl Misak, and others that attempt to de-emphasize or obscure Peirce's representationalism, perhaps to make him more appealing to contemporary analytic "neopragmatists," it is absolutely refreshing to read a book that embraces Peirce's representationalism without apology.However, in the remainder of this review, I will focus on parts that I found troubling. Some of this trouble is probably due more to Peirce himself than to Lane's interpretation of Peirce. But some of it directly concerns Lane's interpretation. In particular, the parts of chapter 6 concerning Peirce's modal realism, while stimulating and enlightening, are also problematic. Further, I do not think that Lane's account of Peirce's idealism appropriately recognizes its similarity to Hegelian or Absolute idealism.To begin with Peirce's modal realism, Lane's discussion of it sets out by addressing the fact that, as Peirce recognizes, the conditionals comprising "pragmatic clarifications," or what result from applying the "pragmatic maxim" to a concept, must be in the hypothetical or subjunctive mood. This is in order to make sense of the truth of even indicative non-conditional propositions such as, to use Peirce's and Lane's example, "the diamond is hard." If the conditionals into which a concept is pragmatically clarified are in the indicative mood... (shrink)

This article provides a response to John Perry and Sarah Lane Ritchie's article, “Magnets Magic, and Other Anomalies: In Defense of Methodological Naturalism.” In so doing, it provides a defense of some of the arguments I made in my article, “Should a Christian Adopt Methodological Naturalism?” I begin by addressing some of the confusion about my position. However, it is not simply my intention to address confusions. There remain some fundamental differences between my position and Perry and Ritchie's. It (...) is on these differences that I wish to focus––differences that enable me to maintain my critique of methodological naturalism without falling prey to the problems they raise. Constructively, I advance the argument that the Christian scientist should be open to the possibility of theology‐engaged science, as well as the science‐engaged theology that Perry and Ritchie advocate. (shrink)

The precise relationships between ideology and cultural policies is a topic of interest to any philosopher concerned with culture. In this fascinating study, the author explores the background of Nazi ideology and policies concerning architecture. Lane persuasively shows how Nazi policies were influenced and inherited from the ideological disputes that surrounded "modern" tendencies in architecture during the Weimar period, especially those disputes concerning the Bauhaus. She also traces the devious paths whereby the social significance of architecture became an issue (...) of national concern in Germany. In the course of the analysis, we not only have a detailed study of architecture and ideology during this crucial period in German history, but a paradigm for intellectual history at its best.--R. J. B. (shrink)

This new edition of Introduction to Lattices and Order presents a radical reorganization and updating, though its primary aim is unchanged. The explosive development of theoretical computer science in recent years has, in particular, influenced the book's evolution: a fresh treatment of fixpoints testifies to this and Galois connections now feature prominently. An early presentation of concept analysis gives both a concrete foundation for the subsequent theory of complete lattices and a glimpse of a methodology for data analysis that is (...) of commercial value in social science. Classroom experience has led to numerous pedagogical improvements and many new exercises have been added. As before, exposure to elementary abstract algebra and the notation of set theory are the only prerequisites, making the book suitable for advanced undergraduates and beginning graduate students. It will also be a valuable resource for anyone who meets ordered structures. (shrink)

Neuronal aggregates involved in conscious awareness are not evenly distributed throughout the CNS but comprise key components referred to as the neural network correlates of consciousness (NNCC). A critical node in this network is the posterior cingulate, precuneal, and retrosplenial cortices. The cytological and neurochemical composition of this region is reviewed in relation to the Brodmann map. This region has the highest level of cortical glucose metabolism and cytochrome c oxidase activity. Monkey studies suggest that the anterior thalamic projection likely (...) drives retrosplenial and posterior cingulate cortex metabolism and that the midbrain projection to the anteroventral thalamic nucleus is a key coupling site between the brainstem system for arousal and cortical systems for cognitive processing and awareness. The pivotal role of the posterior cingulate, precuneal, and retrosplenial cortices in consciousness is demonstrated with posterior cingulate epilepsy cases, midcingulate lesions that de-afferent this region and are associated with unilateral sensory neglect, observations from stroke and vegetative state patients, alterations in blood flow during sleep, and the actions of general anesthetics. Since this region is critically involved in self reflection, it is not surprising that it is similarly a site for the NNCC. Interestingly, information processing during complex cognitive tasks and during aversive sensations such as pain induces efforts to terminate self reflection and result in decreased processing in posterior cingulate and precuneal cortices. (shrink)

Muzykalʹnai︠a︡ ėstetika i kulʹturologii︠a︡ -- Istorii︠a︡ muzyki -- Istorii︠a︡, teorii︠a︡ muzykalʹnogo ispolnitelʹstva -- Tradit︠s︡ionnai︠a︡ kulʹtura.

Fārābī; Avicenna, 980-1037; Avempace, -1138 or 1139; logic; Islamic philosophy; history.